Gamma-Tocotrienol and Hydroxy-Chavicol Synergistically Inhibits Growth of Human Glioma cells.
Ever wonder what would be the effect of combining Vitamin E and Piper Betle (daun sireh in Malay) in terms of their medicinal properties? Well, wonder no more. The team from UMBI led by our very own anti-oxidant expert, Professor Dato’ Dr. Wan Zurinah, has shown that the combination of gamma-tocotrienol and hydroxyl-chavicol (a major bioactive compound in Piper betle) inhibits the growth of human glioma cells by inducing cell death or apoptosis. This research is part of the Higher Institution Centre of Excellence (HICOE) project on Cancer Biomarkers. The post-graduate PhD student who carried out the work is Ms Amirah Abdul Rahman. The results are published in the journal BMC Complementary and Alternative Medicine which carries an impact factor of 2.08. Congratulations to the group!